Cat #: 55-8043XB
Caprico Biotechnologies 1120195 CD4 iFluor700 Antibody, Clone SK3, Mouse IgG1,k, 100 Tests/Unit
Cat #: 55-8043XB
Caprico Biotechnologies 1120195 CD4 iFluor700 Antibody, Clone SK3, Mouse IgG1,k, 100 Tests/Unit
Clone SK3, Mouse IgG1,k
100 Tests/Unit
Brand: Caprico Biotechnologies- This mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
- Utilizes iFluor fluorescent labeling optimized for extremely strong fluorescence
- Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
- >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
- More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.
$294.90
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Clone SK3, Mouse IgG1,k
100 Tests/Unit
Brand: Caprico Biotechnologies- This mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
- Utilizes iFluor fluorescent labeling optimized for extremely strong fluorescence
- Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
- >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
- More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.
The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).
iFluor fluorophores are optimized for strong fluorescence, high photostability and pH independence on proteins. They are avaialble to span the full UV-visible-IR spectrum. iFluor700 is a great alternative to Alexa Fluor® 700. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.
Conjugation | iFluor700 |
---|---|
Excitation Laser | Red (633nm) |
Reactivity | Human |
Host | Mouse |
Antigen | CD4 |
Clone | SK3 |
Isotype | IgG1,k |
Status | RUO |
Size | 100 Tests/Unit |
Storage | 2-8°C and protected from prolonged exposure to light |
Formulation | PBS, pH7.2, 0.09% NaN3 and 0.2% (w/v) BSA |
Immunogen | Human peripheral blood T cells |
Clonality | Monoclonal |
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