Sodium Dodecyl Sulfate (SDS) is an anionic detergent with applications in SDS-PAGE protein analysis and nucleic acid purification. SDS is a wetting agent that is effective in both acid and alkaline solutions, and is most often used as a protein and lipid solubilization reagent. SDS is also a powerful protein denaturant. Popular anionic detergent for a variety of protein methods. Especially useful for denaturing polyacrylamide gel electrophoresis (SDS-PAGE), common component of cell lysis buffers.