Cat #: 08-013
PolyPlus-transfection 101000173 LipidBrick® IM21.7c, Cationic Lipid For LNP Formulation, 250mg/Unit
Cat #: 08-013
PolyPlus-transfection 101000173 LipidBrick® IM21.7c, Cationic Lipid For LNP Formulation, 250mg/Unit
Cationic Lipid For LNP Formulation
250mg/Unit
Brand: Polyplus-transfection- Efficiently modulate LNP properties to tailor biodistribution to the therapeutic purpose
- Secure by using a unique lipid structure protected by an independent patent owned by Polyplus®
- In vitro and in vivo proof of concept have been successfully performed
$1,093.00
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Cationic Lipid For LNP Formulation
250mg/Unit
Brand: Polyplus-transfection- Efficiently modulate LNP properties to tailor biodistribution to the therapeutic purpose
- Secure by using a unique lipid structure protected by an independent patent owned by Polyplus®
- In vitro and in vivo proof of concept have been successfully performed
LipidBrick® IM21.7c is a novel cationic lipid dedicated to the formulation of lipid nanoparticles (LNPs) for the development of mRNA-based vaccines and therapeutics. LipidBrick® IM21.7c overcomes the challenges proposed by the current generation of ionisable lipids used in LNPs, allowing for wider in vivo biodistribution and reduced accumulation in the liver. Proof-of-concept work has demonstrated that the intrinisc properties of LipidBrick® IM21.7c in modulating the overall electrical charge of LNPs extend the in vivo biodistribution and improve both drug efficacy and formulation stability without inducing safety concerns.
| Shelf Life | 24 Months |
|---|---|
| Storage Condition | -20 ± 5°C |
| Weight | 0.077 lbs. (35g) |
| Dimensions | 3.54 L x 2.4 W x 1.2 H in (9 L x 6 W x 3 H cm) |
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