The RNA Clean & Concentrator™-5 provides a simple and reliable method for the rapid preparation of high-quality RNA. This simple procedure is based on the use of a unique single-buffer system and Fast-Spin column technology. The procedure is easy: just add the binding buffer to your sample, adjust the conditions for binding by adding ethanol, wash, and elute the concentrated RNA. RNAs as small as 17 bases can be safely treated and recovered using these kits. The result is highly-concentrated, purified RNA that is suitable for subsequent RNA-based methods including RT-PCR, hybridization, etc.

Typically, up to 5 µg of RNA is eluted into as little as 6-10 µl RNase-free water allowing for a highly concentrated sample.